ChemicalBook > CAS DataBase List > 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Product Name
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS No.
63234-80-0
Chemical Name
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Synonyms
3-(2-Chloroethyl)-6;Risperidone Impurity L;Paliperidone Impurity 26;Risperidone EP IMpurity L;Risperidone Chloro IMpurity;Risperidone Intermediate III;3-(2-Chloro-ethyl)-2-methyl-6,7,8,9-tetrahydro-;Risperidone Impurity 12(Risperidone EP Impurity L);-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one;Risperidone EP Impurity L (Risperidone Chloroethyl Impurity)
CBNumber
CB0359227
Molecular Formula
C11H15ClN2O
Formula Weight
226.7
MOL File
63234-80-0.mol
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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Property

Melting point:
68.5-69.5 °C
Boiling point:
337 °C
Density 
1.30
Flash point:
157 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
3.58±0.70(Predicted)
color 
White to Off-White
InChIKey
CMWCQQUYLPYOMY-UHFFFAOYSA-N
CAS DataBase Reference
63234-80-0(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
HS Code 
2933.99.9701
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2433
Product name
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$124
Updated
2024/03/01
TCI Chemical
Product number
C2433
Product name
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$374
Updated
2024/03/01
TRC
Product number
C366155
Product name
3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
Packaging
5g
Price
$245
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20229
Product name
3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
Packaging
250g
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0020290
Product name
3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO [1,2-A] PYRIMIDINE-4-ONE
Purity
95.00%
Packaging
1G
Price
$739.2
Updated
2021/12/16
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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Palladium hydroxide Toluene Phosphorus oxychloride Ethyl acetate Hydrochloric acid Hydrogen Dichloromethane 2-Acetylbutyrolactone 2-Aminopyridine Isopropyl alcohol PETROLEUM ETHER

Preparation Products

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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Suppliers

Americas 1 Canada 2 China 220 Europe 3 Germany 6 India 38 Japan 2 Switzerland 2 Ukraine 1 United Kingdom 12 United States 38 Global 325
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10658
Advantage
60
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14336
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10413
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
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View Lastest Price from 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-(2-Chloroethyl)-2-Methyl-6,7,8,9-Tetrahydro-4H-Pyrido[1,2-a]-Pyrimidin-4-One 63234-80-0
Price
US $21.00/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-04-30
Shaanxi Haibo Biotechnology Co., Ltd
Product
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 63234-80-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-31
Career Henan Chemical Co
Product
3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4h-pyrido-(1,2-a) pyrimidin-4-one 63234-80-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-07-26

63234-80-0, 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-oneRelated Search:

Methyl 2-hydroxyethyl cellulose Methyl acrylate 2,6-Lutidine Thiophanate-methyl Azamethiphos 4-Methylpyridine METHYL THIOPHENE-2-CARBOXYLATE Methyl acetate 2-Chloro-5-chloromethylpyridine Kresoxim-methyl Bensulfuron methyl Pirimiphos-methyl Methylparaben Methyl 2,4-Difluorobenzoyl Risperidone IMpurity Desfluoro Risperidone Risperidone Pyrimidinone-N-oxide 6-Fluoro-3-[1-bis-[2-(methyl-6,7,8,9-tetrahydropyridol[1,2,a]pyrimidin-4-one-3-yl)ethyl]piperidinium]benzisoxazole Iodide

  • 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]-pyrididine-4-one (intermediate of Risperidone)
  • 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
  • 3-(2-CHLORO-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
  • 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDINO[1,2-A]PYRIMIDINE-4-ONE
  • 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO(1,2A)PYRIMIDINE-4-ONE
  • 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRLDO[1,2-A]PYRIMDIN-4-ONE
  • 3-2(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-alpha]pyrimnidin-4-one
  • 3-2(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]PYRIMDIN-4-ONE
  • 8-(CHLOROETHYL)-9-METHYL-6,10-DIAZABICYCLO[4.4.0]DECA-8,10-DIEN-7-ONE
  • 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-ALPHA]PYRIMIDIN-4-ONE
  • 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2<br>-a]pyrimidin-4-one
  • 3-(2-Chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrimidine-4-one
  • 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1, 2-A]-PYRIMIDIN-4-ONE ( RISPERIDONE INTERMEDIATE ).
  • 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]-PYRIMIDIN-4-ONE(RISPERIDONEINTERMEDIATE)
  • 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]-PYRIDIDINE-4-ONE
  • 3-(2-chloroethyl)-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one
  • Risperidone Intermediate III
  • 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-α]pyrimidin-4-one
  • 3-(2-Chloro-ethyl)-2-methyl-6,7,8,9-tetrahydro-
  • 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
  • 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-
  • 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]-pyrimidin-4-one ,98%
  • 3-(2-Chloroethyl)-6
  • 3-(2-chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]py
  • Phenyl(4-piperidyl)Methanone3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
  • Risperidone Chloro IMpurity
  • Risperidone EP IMpurity L
  • 3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4Hpyrido[1,2-a]pyrimidin-4-one (piperidopyrimidinone intermediate)
  • Paliperidone Impurity 26
  • Risperidone Impurity 12(Risperidone EP Impurity L)
  • 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one &gt
  • -6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
  • Risperidone Impurity L
  • 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one ISO 9001：2015 REACH
  • Risperidone EP Impurity L (Risperidone Chloroethyl Impurity)
  • 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-...
  • TIANFU-CHEM - 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
  • 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, ≥ 98.0%
  • 63234-80-0
  • 63274-80-0
  • 62234-80-0
  • 63274-80-0
  • C11H15ClN2O
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • Intermediates
  • Nucleotides and Nucleosides
  • (intermediate of Risperidone)